Kim Long

Company: ROME Therapeutics

Job title: Vice President, Biology & Translational Sciences

Seminars:

Advancing LINE-1 Reverse Transcriptase Inhibitors in Autoimmune & Neurodegenerative Diseases 9:00 am

Repeat elements like LINE-1 make up most of our DNA, and their expression is silenced in healthy cells When aberrantly expressed in disease, LINE-1 reverse transcriptase (RT) drives interferon signaling and “sterile inflammation” LINE-1 RT inhibitors inhibit tissue interferon signaling and inflammation. They target large patient populations and have the potential to be non-immune suppressive…Read more

day: Day 2